Dr. Frye grew up in western Nebraska and attended Chadron State College for her undergraduate degree. She graduated from Iowa State in 1987 with her veterinary degree and practiced in the Des Moines area until 2023. Dr. Frye is a member of Memorial Lutheran Church of Ames, Cyclone Country Kennel Club, Des Moines Obedience Training Club, Des Moines Golden Retriever Club, Golden Retriever Club of America and the Mid Iowa Retriever Club. These associations allow her to participate in numerous dog sports with her three Golden Retrievers. Dr. Frye and her husband Casey have lived in Ames Since 1984.